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MorHap

CAT: 0804-HY-157172Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157172Size:1 Each
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Description
MorHap is a heroin hapten. MorHap conjugated to tetanus toxoid (TT), palm-CV2, and to monophosphoryl lipid A (MPLA) -containing liposomes partially blocks heroin-induced analgesia and hyperlocomotion in mice. MorHap designed conjugates also significantly inhibits HIV-1 binding to α4β7 receptors. MorHap can be used in research to develop vaccines related to heroin addiction and HIV-1 infection[1].
UNSPSC
12352005
Target
Integrin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
COVID-19-immunoregulation
Field of Research
Infection; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/morhap.html
Solubility
10 mM in DMSO
Smiles
OC1=C(O[C@H]2[C@H](NC(CCSC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)=O)C=C6)C([C@]2(CC7)[C@]6([H])C(N7C)C8)=C8C=C1
Molecular Formula
C39H38N2O3S
Molecular Weight
614.80
References & Citations
[1]Torres OB, et al. Heroin-HIV-1 (H2) vaccine: induction of dual immunologic effects with a heroin hapten-conjugate and an HIV-1 envelope V2 peptide with liposomal lipid A as an adjuvant. NPJ Vaccines. 2017 May 2;2:13.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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