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LFS-1107

CAT: 0804-HY-157136Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157136Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LFS-1107 is a reversible CRM1 inhibitor (Kd: 12.5 pM) . LFS-1107 can selectively eliminate extranodal natural killer/T cell lymphoma (ENKTL) cells and can be used for cancer research[1].
CAS Number
1799330-91-8
UNSPSC
12352005
Target
C-Myc; COX; CRM1; Survivin
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lfs-1107.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=NN=NN1C2=CC=CC=C2)/C=C/CCN=C=S
Molecular Formula
C12H11N5OS2
Molecular Weight
305.38
References & Citations
[1]He Liu, et al. Discovery and biological evaluation of a potent small molecule CRM1 inhibitor for its selective ablation of extranodal NK/T cell lymphoma eLife 12:e80625.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-2

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