ICMT-IN-46

• Description:

  ICMT-IN-46 (compound 25) is an inhibitor of ICMT (IC50=0.556 μM) [1].

• UNSPSC:

  12352005

• Target:

  ICMT

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/icmt-in-46.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1(C)CC(CCNC2=CC=CC(C(C)(C)C)=C2)(C3=CC=CC=C3)CCO1

• Molecular Formula:

  C25H35NO

• Molecular Weight:

  365.55

• References & Citations:

  [1]Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT) . J Med Chem. 2011 Jul 28;54 (14) :5031-47.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1313602-71-9]