ICMT-IN-46

• UNSPSC Description:

  ICMT-IN-46 (compound 25) is an inhibitor of ICMT (IC50=0.556 μM)[1].

• Target Antigen:

  ICMT

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Cancer-programmed cell death

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/icmt-in-46.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1(C)CC(CCNC2=CC=CC(C(C)(C)C)=C2)(C3=CC=CC=C3)CCO1

• Molecular Weight:

  365.55

• References & Citations:

  [1]Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT). J Med Chem. 2011 Jul 28;54(14):5031-47.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1313602-71-9