9-Chloromethyl-10-hydroxy-11-F-Camptothecin

9-Chloromethyl-10-hydroxy-11-F-Camptothecin

• CAS Number: 2414594-22-0
• UNSPSC Description: 9-Chloromethyl-10-hydroxy-11-F-Camptothecin is a novel camptothecin derivatives. 9-Chloromethyl-10-hydroxy-11-F-Camptothecin is a DNA topoisomerase I (Topo I) inhibitor, can be used in anticancer research[1].
• Target Antigen: Topoisomerase
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/9-chloromethyl-10-hydroxy-11-f-camptothecin.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1N2C(C(C(C2)=C(C3=C4)CCl)=NC3=CC(F)=C4C)=CC5=C1COC([C@]5(O)CC)=O
• Molecular Weight: 428.84
• References & Citations: [1]Chari Ravi, et al. Preparation of camptothecin derivatives as antitumor agents. WO2020219287 A1. 2020-10-29
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported