7-Aminomethyl-10-methyl-11-fluoro camptothecin (TFA)
CAT:
804-HY-132160A-04
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
7-Aminomethyl-10-methyl-11-fluoro camptothecin (TFA)
- UNSPSC Description: 7-Aminomethyl-10-methyl-11-fluoro camptothecin TFA is a cytotoxin of MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (HY-132158). 7-Aminomethyl-10-methyl-11-fluoro camptothecin TFA can be used for the synthesis of camptothecin antibody-drug conjugate (ADC)[1].
- Target Antigen: ADC Cytotoxin
- Type: Reference compound
- Related Pathways: Antibody-drug Conjugate/ADC Related
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/7-aminomethyl-10-methyl-11-fluoro-camptothecin-tfa.html
- Purity: 96.52
- Solubility: 10 mM in DMSO
- Smiles: NCC1=C2C(C(N3C2)=CC([C@]4(CC)O)=C(C3=O)COC4=O)=NC5=CC(F)=C(C=C51)C.OC(C(F)(F)F)=O
- Molecular Weight: 523.43
- References & Citations: [1]Li W, et, al. Synthesis and Evaluation of Camptothecin Antibody-Drug Conjugates. ACS Med Chem Lett. 2019 Sep 6;10(10):1386-1392.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, sealed storage, away from moisture and light)
- Clinical Information: No Development Reported