JAK-IN-31

JAK-IN-31

• CAS Number: 2597016-88-9
• UNSPSC Description: JAK-IN-31 (Example 75) is a JAK inhibitor with IC50 ranges of ≤0.01µM, ≤0.01µM, 0.01-0.1 µM and ≤0.01µM for JAK1, JAK2, JAK3 and Tyk2 respectively. JAK-IN-31 can be used in cancer research[1].
• Target Antigen: JAK
• Type: Reference compound
• Related Pathways: Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/jak-in-31.html
• Solubility: 10 mM in DMSO
• Smiles: CC1=NN=C(S1)C2=CN=C3C(C=CN3)=C2N[C@@H]4C[C@@H](C4)NS(=O)(C5=CC(C#N)=CC=C5)=O
• Molecular Weight: 465.55
• References & Citations: [1]David Randolph ANDERSON, et al. Substituted sulfonamide pyrrolopyridines as jak inhibitors. Patent WO2021022178A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported