PDE11A4-IN-1

PDE11A4-IN-1

• CAS Number: 3027607-92-4
• UNSPSC Description: PDE11A4-IN-1 (compound 23b) is a potent and selective PDE11A4 inhibitor with an IC50 of 12 nM. PDE11A4-IN-1 show high selectivity for PDE11A4 over PDE1, PDE2, PDE7, PDE8, and PDE9[1].
• Target Antigen: Phosphodiesterase (PDE)
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/pde11a4-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=C2C(N(N=C2C(F)F)C3=CC=CC=C3)=NC(C4=CC=NN4C)=C1)N(CC)CC
• Molecular Weight: 424.45
• References & Citations: [1]Shams Ul Mahmood, et al. First Optimization of Novel, Potent, Selective PDE11A4 Inhibitors for Age-Related Cognitive Decline. J Med Chem. 2023 Oct 20.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported