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NOX2-IN-1

CAT: 0804-HY-156424Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-156424Size:1 Each
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Description
NOX2-IN-1 (compound 10) is an inhibitor of nicotinamide adenine dinucleotide phosphate oxidase isoform 2 (NOX2) . NOX2-IN-1 targets the p47phox p22phox protein protein interaction with favorable binding affinities and cellular activities[1].
CAS Number
2648709-25-3
UNSPSC
12352005
Target
NADPH Oxidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nox2-in-1.html
Solubility
10 mM in DMSO
Smiles
NC1=NC2=CC=CC(OCCOCCOC3=C4C=CC(N)=NC4=CC=C3)=C2C=C1
Molecular Formula
C22H22N4O3
Molecular Weight
390.44
References & Citations
[1]Haixia Ge, et al. Discovery of Potent and Selective CB2 Agonists Utilizing a Function-Based Computational Screening Protocol. ACS Chem Neurosci. 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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