HIV-IN-9

HIV-IN-9

• UNSPSC Description: HIV-IN-9 (Compound 2b) is a HIV inhibitor (IC50: 6.65 μg/mL), and has high binding affinity with HIV-RT. HIV-IN-9 also inhibits CYP3A4, CYP1A2, CYP2C1, and CYP2D6[1].
• Target Antigen: Cytochrome P450; HIV
• Type: Reference compound
• Related Pathways: Anti-infection;Metabolic Enzyme/Protease
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/hiv-in-9.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N1)C(C)=CN(CC(N2C(C3=CC=C(Cl)C=C3)=NC4=CC=CC=C42)=O)C1=O
• Molecular Weight: 394.81
• References & Citations: [1]Srivastava R, et al. Exploring antiviral potency of N-1 substituted pyrimidines against HIV-1 and other DNA/RNA viruses: Design, synthesis, characterization, ADMET analysis, docking, molecular dynamics and biological activity. Comput Biol Chem. 2023 Oct;106:107910.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported