Products for Research Use Only
RegisterLogin

PK-10

CAT: 0804-HY-156090Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-156090Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PK-10 is a synergistic antibacterial agent of Fluconazole and has strong antifungal activity against a variety of Fluconazole-resistant Candida albicans strains. PK-10 combined with Fluconazole can inhibit hyphae formation and induce the accumulation of reactive oxygen species. It further causes damage to mitochondrial membrane potential, reduces intracellular ATP content, and leads to mitochondrial dysfunction[1].
CAS Number
3074451-41-2
UNSPSC
12352005
Target
Fungal; Mitochondrial Metabolism
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pk-10.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(N2CCN(CC2)CC3=CC=C(C(F)(F)F)C=C3)C=C1)/C=C/C4=CC5=C(N=C4N6CCN(CC6)C)C=CC=C5
Molecular Formula
C35H36F3N5O
Molecular Weight
599.69
References & Citations
[1]Sun A, et al. Optimization and antifungal activity of quinoline derivatives linked to chalcone moiety combined with FLC against Candida albicans. Eur J Med Chem. 2023 Nov 15;260:115782.. .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-153943DNA-PK-IN-10
HY-121648PK 130
HY-110184-01PK-THPP
HY-19567-01PK 11195
HY-146565-01DNA-PK-IN-8
HY-142944DNA-PK-IN-2
HY-P5429-01DNA-PK Substrate
HY-146566DNA-PK-IN-9
HY-163134-01DNA-PK-IN-12
HY-144039DNA-PK-IN-6

Alternative Products

CatalogName
MBS5821370PK-10
MBS5820827DNA-PK-IN-10
6000-090Plug, PK,10-32,5/PK
7002-05-10Frit Assy SS/Pk 250X3 10 Pk
294103MicroMincer Liners, 10 pk
233114510% 12-well PAGEL 10/pk
6000-282RDFittings, PK,1/16, OP, RD,10/PK
6000-282MCFittings, PK,1/16, OP, MC,10/PK
6000-282BLFittings, PK,1/16, OP, BL,10/PK
6000-282YLFittings, PK,1/16, OP, YL,10/PK

Popular Products