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DNA-PK-IN-9

CAT: 0804-HY-146566Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146566Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DNA-PK-IN-9 (compound YK6) is a potent DNA-dependent protein kinase (DNA-PK) inhibitor with an IC50 value of 10.47 nM. DNA-PK-IN-9 can be used for researching anticancer[1].
UNSPSC
12352005
Target
DNA-PK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dna-pk-in-9.html
Solubility
10 mM in DMSO
Smiles
CC1=CC2=C(C=C1NC3=NC=C4C(C5(C(N4C)=O)CCOCC5)=N3)C=CC=N2
Molecular Formula
C21H21N5O2
Molecular Weight
375.42
References & Citations
[1]Ding Z, et al. Discovery of novel 7,8-dihydropteridine-6 (5H) -one-based DNA-PK inhibitors as potential anticancer agents via scaffold hopping strategy. Eur J Med Chem. 2022;237:114401.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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