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5-Hydroxydecanoic acid

CAT: 0804-HY-155941Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-155941Size:1 Each
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Description
5-Hydroxydecanoic acid (5-HD) is a KATP channel antagonist, which has the effect of blocking the K KATP channel only during ischaemia by competing with the ATP binding site and does not affect pancreatic KATP channels[1].
CAS Number
624-00-0
UNSPSC
12352211
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/5-hydroxydecanoic-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(CCCC(CCCCC)O)O
Molecular Formula
C10H20O3
Molecular Weight
188.26
References & Citations
[1]J A Auchampach, et al. Blockade of ischaemic preconditioning in dogs by the novel ATP dependent potassium channel antagonist sodium 5-hydroxydecanoate. Cardiovasc Res. 1992 Nov;26 (11) :1054-62.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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