5-Hydroxydecanoic acid

• Description:

  5-Hydroxydecanoic acid (5-HD) is a KATP channel antagonist, which has the effect of blocking the K KATP channel only during ischaemia by competing with the ATP binding site and does not affect pancreatic KATP channels[1].

• UNSPSC:

  12352211

• Target:

  Potassium Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/5-hydroxydecanoic-acid.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(CCCC(CCCCC)O)O

• Molecular Formula:

  C10H20O3

• Molecular Weight:

  188.26

• References & Citations:

  [1]J A Auchampach, et al. Blockade of ischaemic preconditioning in dogs by the novel ATP dependent potassium channel antagonist sodium 5-hydroxydecanoate. Cardiovasc Res. 1992 Nov;26 (11) :1054-62.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [624-00-0]