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DMPE-PEG1000 (ammonium)

CAT: 0804-HY-155927Size: 1 EachDry Ice: NoHazardous: No
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Description
DMPE-PEG1000 ammonium (14:0 PEG1000 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
CAS Number
474922-82-2
Product Name Alternative
14:0 PEG1000 PE (ammonium) ; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy (polyethylene glycol) -1000] (ammonium)
UNSPSC
12352200
Target
Liposome
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/14-0-peg1000-pe.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCOP(O)(OC[C@@H](COC(CCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCC)=O)=O)OCCOC.N.[n]
Molecular Formula
(C2H4O) nC35H68NO10P.NH3
Molecular Weight
1000 (Average)
References & Citations
[1]Kandel PK, et al. Incorporating functionalized polyethylene glycol lipids into reprecipitated conjugated polymer nanoparticles for bioconjugation and targeted labeling of cells. Nanoscale. 2011 Mar;3 (3) :1037-45.
Shipping Conditions
Room temperature
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

Chemical Information

CID 156594148
CAS Number474922-82-2
PubChem CID156594148
IUPAC Nameazane;[3-[hydroxy-[2-(2-methoxyethoxycarbonylamino)ethoxy]phosphoryl]oxy-2-tetradecanoyloxypropyl] tetradecanoate
Molecular FormulaC37H75N2O11P
Molecular Weight755.0
Topological Polar Surface Area157
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count12
Rotatable Bond Count40
Heavy Atom Count51
Formal Charge0
Complexity861
SMILES
CCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)OCCOC)OC(=O)CCCCCCCCCCCCC.N
InChI
InChI=1S/C37H72NO11P.H3N/c1-4-6-8-10-12-14-16-18-20-22-24-26-35(39)46-32-34(33-48-50(42,43)47-29-28-38-37(41)45-31-30-44-3)49-36(40)27-25-23-21-19-17-15-13-11-9-7-5-2;/h34H,4-33H2,1-3H3,(H,38,41)(H,42,43);1H3
InChIKey
DJYTWZDTQHDVBC-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of CID 156594148
CAS: 474922-82-2
CID: 156594148
Formula: C37H75N2O11P
MW: 755.0
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight755.0
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count12
Rotatable Bond Count40
Exact Mass754.51084821
Monoisotopic Mass754.51084821
Topological Polar Surface Area157 Ų
Heavy Atom Count51
Formal Charge0
Complexity861
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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