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Antifungal agent 60

CAT: 0804-HY-155545Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-155545Size:1 Each
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Description
Antifungal agent 60 (compound 16) is an inhibitor of ergosterol biosynthesis with broad-spectrum antifungal activity. Antifungal agent 60 inhibits 7 human pathogenic fungal species, 2 fluconazole-resistant C. albicans isolates and 2 multi-drug resistant Candida auris isolates. Antifungal agent 60 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
9007-83-4
UNSPSC
12352005
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antifungal-agent-60.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC=C(C=C1)C#CCO[C@H](C)[C@@](C2=CC=C(C=C2F)F)(CN3N=CN=C3)O
Molecular Formula
C22H18F2N4O2
Molecular Weight
408.40
References & Citations
[1]Xie F, et al. Novel antifungal triazoles with alkynyl-methoxyl side chains: Design, synthesis, and biological activity evaluation. Eur J Med Chem. 2023 Sep 5;257:115506.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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