PEX5-PEX14 PPI-IN-2

PEX5-PEX14 PPI-IN-2

• UNSPSC Description: PEX5-PEX14 PPI-IN-2 (compound 12) is a PEX14-PEX5 protein-protein interaction (PPI) inhibitor. PEX5-PEX14 PPI-IN-2 inhibits PEX14-PEX5 PPI with EC50 values of 5 and 17 µM in T. b. brucei and HepG2 cells, respectively. PEX5-PEX14 PPI-IN-2 can be used in the research of diseases related to trypanosome infection[1].
• Target Antigen: Biochemical Assay Reagents
• Type: Reference compound
• Related Pathways: Others
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/pex5-pex14-ppi-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(OC)[C@@H](N1C[C@H](CC2=CNC3=C2C=CC=C3)NC(C1)=O)CC4=CNC5=C4C=CC=C5
• Molecular Weight: 430.50
• References & Citations: [1]Marciniak M, et al. Development of novel PEX5-PEX14 protein-protein interaction (PPI) inhibitors based on an oxopiperazine template. Eur J Med Chem. 2023 Oct 5;258:115587.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported