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HA-IN-1

CAT: 0804-HY-155514Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-155514Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HA-IN-1 (compound 5g) is a Hemagglutinin (HA) ligand with high affinity, targeting to the trypsin cleavage site of HA. HA-IN-1 inhibits HA-mediated membrane fusion and reduces the pulmonary virus titer in vivo. HA-IN-1 is a potential influenza A virus (IAV) inhibitor, and an anti-influenza agent[1].
UNSPSC
12352005
Target
Influenza Virus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ha-in-1.html
Solubility
10 mM in DMSO
Smiles
CC1=CC(C(C)=O)=C(O)C(CC2=C(CC3=C(O)C(C)=CC(C(C)=O)=C3O)C4=CC(C5=C6C(C=CC=C6)=CC7=C5C=CC=C7)=CC=C4N2)=C1O
Molecular Formula
C42H35NO6
Molecular Weight
649.73
References & Citations
[1]Li B, et al. Design, synthesis, and biological evaluation of novel penindolone derivatives as potential inhibitors of hemagglutinin-mediated membrane fusion. Eur J Med Chem. 2023 Oct 5;258:115615.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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MBS6479365-01HA-1 (HLA-HA1, HMHA1, KIAA0223, Minor Histocompatibility Antigen HA-1, mHag HA-1, Minor Histocompatibility Protein HA-1) (APC)
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