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CYP2A6-IN-1

CAT: 0804-HY-155456Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-155456Size:1 Each
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Description
CD-6 is a flavonoid CYP2A6 inhibitor (IC50: 1.566 μM) . CYP2A6 inhibits the metabolism of nicotine to cotinine, resulting in an increase in the amount of nicotine available in the blood, leading to increased smoking behavior. CD-6 mediates CYP2A6 inhibition and can be used in research on smoking cessation or smoking-related diseases[1].
UNSPSC
12352005
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cyp2a6-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C(C2=CC=CC=C2OCC(O)=O)OC3=CC=CC=C31
Molecular Formula
C17H12O5
Molecular Weight
296.27
References & Citations
[1]Goyal N et al. Design, Synthesis, and Biological Studies of Flavone-Based Esters and Acids as Potential P450 2A6 Inhibitors. Chem Res Toxicol. 2023 Nov 14.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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