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APS3

CAT: 0804-HY-155381Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-155381Size:1 Each
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Description
APS3 is a GABA and nACh receptors inhibitor, with a LC50 of 7.2423 μg/mL against Plutella xylostella[1].
CAS Number
1225373-70-5
UNSPSC
12352005
Target
GABA Receptor; nAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/aps3.html
Solubility
10 mM in DMSO
Smiles
FC(F)(F)C1=CC(Cl)=C(N2N=C(C#N)C(S(C(F)(F)F)=O)=C2NS(C3=CC=C([N+]([O-])=O)C=C3)(=O)=O)C(Cl)=C1
Molecular Formula
C18H7Cl2F6N5O5S2
Molecular Weight
622.31
References & Citations
[1]Yueyue Xu, et al. Design and One-Pot Ultrasound Synthesis of Inorganic Base-Promoted Fluorescent Ligand-Gated Ion Channel Fused Arylpyrazole Sulfonamide Skeletons to Enhance Phloem Mobility and Insecticidal Activity as GABA and nACh Receptors Inhibitors. J Agric Food Chem. 2023 Nov 1;71 (43) :16331-16351.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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