4-Thiouridine 5′-triphosphate (tetrasodium)
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804-HY-154840A
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

4-Thiouridine 5′-triphosphate (tetrasodium)
- CAS Number: 68507-49-3
- UNSPSC Description: 4-Thiouridine 5′-triphosphate (4-Thio-UTP) tetrasodium is a potent P2Y2 and P2Y4 receptor agonist, with EC50s of 35 and 350 nM for hP2Y2 and hP2Y4, respectively. 4-Thiouridine 5′-triphosphate tetrasodium can be used in the study of crosslinking experiments, labeling of transcriptional complex[1][2].
- Target Antigen: P2Y Receptor
- Type: Reference compound
- Related Pathways: GPCR/G Protein
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/4-thiouridine-5-triphosphate-tetrasodium.html
- Solubility: 10 mM in DMSO
- Smiles: O[C@H]1[C@@H](O)[C@H](N2C(NC(C=C2)=S)=O)O[C@@H]1COP(OP(OP(O[Na])(O[Na])=O)(O[Na])=O)(O[Na])=O
- Molecular Weight: 588.13
- References & Citations: [1]Jacobson KA, et, al. Structure activity and molecular modeling analyses of ribose- and base-modified uridine 5'-triphosphate analogues at the human P2Y2 and P2Y4 receptors. Biochem Pharmacol. 2006 Feb 14;71(4):540-9.|[2]Bartholomew B, et, al. RNA contacts subunits IIo and IIc in HeLa RNA polymerase II transcription complexes. J Biol Chem. 1986 Oct 25;261(30):14226-31.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported