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Homouridine

CAT: 0804-HY-154698Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-154698Size:1 Each
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Description
Homouridine, is an uridine analogue. Homouridine serves as an intermediate to prepare MMP-2 inhibitor (compund I, IC50=150 μM) . Homouridine derivate (compund I) also inhibits TNF-α binding to TNF-αR1[1].
CAS Number
30685-57-5
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/homouridine.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@H](O)[C@@H](CCO)O[C@H]1N(C(N2)=O)C=CC2=O
Molecular Formula
C10H14N2O6
Molecular Weight
258.23
References & Citations
[1]Hsu Li-Wei, et al. Uridine derivatives as matrix metalloproteinase (MMP) and tumor necrosis factor (TNF) inhibitors for the treatment of cancer. European Patent Organization, EP1338282 A1. 2003-08-27.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

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