5’-Deoxy-N4,N4-dimethyl-5-fluorocytidine

5’-Deoxy-N4,N4-dimethyl-5-fluorocytidine

• CAS Number: 933443-84-6
• UNSPSC Description: 5’-Deoxy-N4,N4-dimethyl-5-fluorocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/5-deoxy-n4-n4-dimethyl-5-fluorocytidine.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1N=C(N(C)C)C(F)=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](C)O2
• Molecular Weight: 273.26
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported