5’-Deoxy-N4,N4-dimethyl-5-fluorocytidine

• CAS Number:

  933443-84-6

• UNSPSC Description:

  5’-Deoxy-N4,N4-dimethyl-5-fluorocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/5-deoxy-n4-n4-dimethyl-5-fluorocytidine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1N=C(N(C)C)C(F)=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](C)O2

• Molecular Weight:

  273.26

• References & Citations:

  [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported