3′-O-[(1,1-Dimethylethyl)dimethylsilyl]-2′-O-methyluridine

• UNSPSC Description:

  3′-O-[(1,1-Dimethylethyl)dimethylsilyl]-2′-O-methyluridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/3-o-1-1-dimethylethyl-dimethylsilyl-2-o-methyluridine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC[C@@H]1[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H](OC)[C@H](N2C(NC(C=C2)=O)=O)O1

• Molecular Weight:

  372.49

• References & Citations:

  [1]Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  171268-84-1