3′-O-[(1,1-Dimethylethyl)dimethylsilyl]-2′-O-methyluridine

3′-O-[(1,1-Dimethylethyl)dimethylsilyl]-2′-O-methyluridine

• CAS Number: 171268-84-1
• UNSPSC Description: 3′-O-[(1,1-Dimethylethyl)dimethylsilyl]-2′-O-methyluridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/3-o-1-1-dimethylethyl-dimethylsilyl-2-o-methyluridine.html
• Solubility: 10 mM in DMSO
• Smiles: OC[C@@H]1[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H](OC)[C@H](N2C(NC(C=C2)=O)=O)O1
• Molecular Weight: 372.49
• References & Citations: [1]Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported