3’-O-Me-C(Bz)-2’-phosphoramidite

CAT:

804-HY-154481

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CAS Number: 179479-03-9
UNSPSC Description: 3’-O-Me-C(Bz)-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen: Nucleoside Antimetabolite/Analog
Type: Oligonucleotides
Related Pathways: Cell Cycle/DNA Damage
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/3-o-me-c-bz-2-phosphoramidite.html
Solubility: 10 mM in DMSO
Smiles: O=C(NC(NC(C1=CC=CC=C1)=O)C=C2)N2[C@@H]3O[C@H](COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)[C@@H](OC)[C@H]3OP(OCCC#N)P(C(C)C)C(C)C
Molecular Weight: 882.92
References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

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