2′,5′-Dideoxy-5′-iodouridine

2′,5′-Dideoxy-5′-iodouridine

• CAS Number: 58510-66-0
• UNSPSC Description: 2′,5′-Dideoxy-5′-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/2-5-dideoxy-5-iodouridine.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C=C1)NC(N1[C@@H]2O[C@H](CI)[C@@H](O)C2)=O
• Molecular Weight: 338.10
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported