5’-O-(4,4’-Dimethoxytrityl)-2’-O-(2-methoxyethyl) adenosine

5’-O-(4,4’-Dimethoxytrityl)-2’-O-(2-methoxyethyl) adenosine

• CAS Number: 1384253-67-1
• UNSPSC Description: 5’-O-(4,4’-Dimethoxytrityl)-2’-O-(2-methoxyethyl) adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/5-o-4-4-dimethoxytrityl-2-o-2-methoxyethyl-adenosine.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]1[C@@H](OCCOC)[C@H](N2C(N=CN=C3N)=C3N=C2)O[C@@H]1COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6
• Molecular Weight: 627.69
• References & Citations: [1]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported