N1-Ethyl-2’-O-TBDMS-5’-O-DMTr-3’-phosphoramidite

CAT:

804-HY-154342

Size:

Inquire

Price:

Ask

For price, please contact [email protected]

UNSPSC Description: N1-Ethyl-2’-O-TBDMS-5’-O-DMTr-3’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen: Nucleoside Antimetabolite/Analog
Type: Oligonucleotides
Related Pathways: Cell Cycle/DNA Damage
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/n1-ethyl-2-o-tbdms-5-o-dmtr-3-phosphoramidite.html
Solubility: 10 mM in DMSO
Smiles: O=C(NC1=O)N(CC)C=C1[C@@H]2O[C@H](COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)[C@@H](OP(N(C(C)C)C(C)C)OCC[N+]#[C-])[C@H]2O[Si](C)(C)C(C)(C)C
Molecular Weight: 889.10
References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-154342	N1-Ethyl-2’-O-TBDMS-5’-O-DMTr-3’-phosphoramidite
HY-154264	5’-O-DMTr-N6-ethyl-2’-deoxyadenosine 3’-CED phosphoramidite
HY-154366-04	5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite
HY-154366-02	5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite
HY-154366-01	5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite
HY-154366-03	5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite
HY-154238	5’-O-DMTr-3’-deoxyuridine 2’-CED phosphoramidite
HY-W010681A	3'-O-DMTr-thymidine 5'-CE phosphoramidite
HY-134337	5'-O-DMTr-3'-O-methyl uridine-3'-CED-phosphoramidite
HY-W545104-03	N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite

Cat	Name
TNU1141-5mg	N1-Ethyl-2’-O-TBDMS-5’-O-DMTr-3’-phosphoramidite
TNU1141-50mg	N1-Ethyl-2’-O-TBDMS-5’-O-DMTr-3’-phosphoramidite
TNU1141-1mg	N1-Ethyl-2’-O-TBDMS-5’-O-DMTr-3’-phosphoramidite
TNU1141-10mg	N1-Ethyl-2’-O-TBDMS-5’-O-DMTr-3’-phosphoramidite
TNU1141-1g	N1-Ethyl-2’-O-TBDMS-5’-O-DMTr-3’-phosphoramidite
TNU0961-1mg	5’-O-DMTr-2’-O-TBDMS-N1-methylpseudouridine-3’-(cyanoethyl-N,N-d
TNU0961-50mg	5’-O-DMTr-2’-O-TBDMS-N1-methylpseudouridine-3’-(cyanoethyl-N,N-d
TNU0961-10mg	5’-O-DMTr-2’-O-TBDMS-N1-methylpseudouridine-3’-(cyanoethyl-N,N-d
TNU0961-5mg	5’-O-DMTr-2’-O-TBDMS-N1-methylpseudouridine-3’-(cyanoethyl-N,N-d
TNU0961-1g	5’-O-DMTr-2’-O-TBDMS-N1-methylpseudouridine-3’-(cyanoethyl-N,N-d