2’,3’-Isopropylidene-5-hydroxyuridine

2’,3’-Isopropylidene-5-hydroxyuridine

• CAS Number: 20406-82-0
• UNSPSC Description: 2’,3’-Isopropylidene-5-hydroxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/2-3-isopropylidene-5-hydroxyuridine.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C(O)=CN1[C@H]2[C@H](OC(C)(C)O3)[C@H]3[C@@H](CO)O2)NC1=O
• Molecular Weight: 300.26
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported