5′-O-[Bis(4-methoxyphenyl)phenylmethyl]cytidine

• UNSPSC Description:

  5′-O-[Bis(4-methoxyphenyl)phenylmethyl]cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/5-o-bis-4-methoxyphenyl-phenylmethyl-cytidine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@@H]1[C@H](O)[C@@H](COC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)O[C@H]1N5C=CC(N)=NC5=O

• Molecular Weight:

  545.58

• References & Citations:

  [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  112897-99-1