3’-Beta-C-Methyl-5-trifluoromethyluridine

• UNSPSC Description:

  3’-Beta-C-Methyl-5-trifluoromethyluridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/3-beta-c-methyl-5-trifluoromethyluridine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@@H]1[C@](O)(C)[C@@H](CO)O[C@H]1N(C(N2)=O)C=C(C(F)(F)F)C2=O

• Molecular Weight:

  326.23

• References & Citations:

  [1]Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported