2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate (ammonium)

2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate (ammonium)

• UNSPSC Description: 2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate (ammonium) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/2-o-2-methoxyethyl-guanosine-5-triphosphate-ammonium.html
• Solubility: 10 mM in DMSO
• Smiles: O=P(OP(O)(OP(O)(O)=O)=O)(O)OC[C@@H]1[C@@H](O)[C@@H](OCCOC)[C@H](N(C=N2)C3=C2C(NC(N)=N3)=O)O1.N.N.N.N
• Molecular Weight: 649.38
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported