N4-Benzoyl-5-methyl-2’-O,4’-C-methylenecytidine

N4-Benzoyl-5-methyl-2’-O,4’-C-methylenecytidine

• CAS Number: 206055-81-4
• UNSPSC Description: N4-Benzoyl-5-methyl-2’-O,4’-C-methylenecytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/n4-benzoyl-5-methyl-2-o-4-c-methylenecytidine.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1N=C(NC(C2=CC=CC=C2)=O)C(C)=CN1[C@H]3[C@]4([H])OC[C@]([C@H]4O)(CO)O3
• Molecular Weight: 373.36
• References & Citations: [1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported