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JHDM-IN-1

CAT: 0804-HY-153608Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-153608Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JHDM-IN-1 (Compound 1) is a Jumonji C domain-containing HDMs (JHDM) inhibitor with IC50s of 3.4, 4.3, 5.9, 10 and 43 μM against JMJD2C, JMJD2A, JMJD2E, PHF8 and JMJD3, respectively[1].
CAS Number
1310809-17-6
UNSPSC
12352005
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/jhdm-in-1.html
Purity
97.60
Solubility
DMSO : 100 mg/mL (ultrasonic; warming)
Smiles
OC(/C=C/C(N(O)CCCCNCC(C=C1)=CC=C1COC(NC2=CC=CC3=C2C=CC=C3)=O)=O)=O
Molecular Formula
C27H29N3O6
Molecular Weight
491.54
References & Citations
[1]Luo X, et al. A selective inhibitor and probe of the cellular functions of Jumonji C domain-containing histone demethylases. J Am Chem Soc. 2011 Jun 22;133 (24) :9451-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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