N4-Desmethyl-N5-Methyl wyosine

N4-Desmethyl-N5-Methyl wyosine

• CAS Number: 59327-63-8
• UNSPSC Description: N4-Desmethyl-N5-Methyl wyosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/n4-desmethyl-n5-methyl-wyosine.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]1[C@@H](O)[C@H](N(C=N2)C3=C2C(N4C(N(C)C(C)=C4)=N3)=O)O[C@@H]1CO
• Molecular Weight: 335.32
• References & Citations: [1]Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported