N4,N4-Dimethylarabinocytidine

N4,N4-Dimethylarabinocytidine

• CAS Number: 82855-64-9
• UNSPSC Description: N4,N4-Dimethylarabinocytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/n4-n4-dimethylarabinocytidine.html
• Solubility: 10 mM in DMSO
• Smiles: OC[C@@H]1[C@@H](O)[C@H](O)[C@H](N2C=CC(N(C)C)=NC2=O)O1
• Molecular Weight: 271.27
• References & Citations: [1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported