5’(R)-C-Methylcytidine

5’(R)-C-Methylcytidine

• CAS Number: 72159-53-6
• UNSPSC Description: 5’(R)-C-Methylcytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/5-r-c-methylcytidine.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H](C)[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(N)C=C2)=O)O1
• Molecular Weight: 257.24
• References & Citations: [1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported