6-(2-O-Methyl-beta-D-ribofuranosyl)-3-(2-oxo-propyl)-6H-imidazo[1,2-c]pyrimidin-5-one

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804-HY-152770

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CAS Number: 2095417-54-0
UNSPSC Description: 6-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-3-(2-oxopropyl)imidazo[1,2-c]pyrimidin-5(6H)-one is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen: Nucleoside Antimetabolite/Analog
Type: Oligonucleotides
Related Pathways: Cell Cycle/DNA Damage
Applications: Cancer-programmed cell death
Field of Research: Others
Assay Protocol: https://www.medchemexpress.com/6-2-o-methyl-beta-d-ribofuranosyl-3-2-oxo-propyl-6h-imidazo-1-2-c-pyrimidin-5-one.html
Solubility: 10 mM in DMSO
Smiles: O=C1N2C(C=CN1[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3OC)=NC=C2CC(C)=O
Molecular Weight: 337.33
References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-152770	6-(2-O-Methyl-beta-D-ribofuranosyl)-3-(2-oxo-propyl)-6H-imidazo[1,2-c]pyrimidin-5-one
HY-154730	9-(2’-O-Acetyl-5’-O-benzoyl-3’-O-methyl-beta-D-ribofuranosyl)-6-chloropurine
HY-154029	3-β-D-Ribofuranosyl-6-hydroxymethyl-furano[2,3-d]-pyrimidin-2-one
HY-154416	5-(2,3,5-Tri-O-benzyl-beta-D-ribofuranosyl)-3-methyl-2-benzyloxypyridine
HY-152405	6-Amino-1,2-dihydro-2-β-D-ribofuranosyl-4H-pyrazolo[3,4-d]pyrimidin-4-one
HY-152655	6-Ethoxy-9-beta-D-(2-C-methyl-ribofuranosyl)purine
HY-154731	9-(2’-O-Acetyl-5’-O-benzoyl-3’-O-methyl-beta-D-ribofuranosyl)-2,6-dichloropurine
HY-154440	2-Amino-6-chloro-9-(3’-O-methyl-beta-D-ribofuranosyl)-9H-purine
HY-154475	9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine
HY-152982	1-(2-C-β-Methyl-β-D-ribofuranosyl)-5-nitropyridine-2(1H)-one

Cat	Name
TNU0005-1mg	6-(2-O-Methyl-beta-D-ribofuranosyl)-3-(2-oxo-propyl)-6H-imidazo[
TNU0005-10mg	6-(2-O-Methyl-beta-D-ribofuranosyl)-3-(2-oxo-propyl)-6H-imidazo[
TNU0005-50mg	6-(2-O-Methyl-beta-D-ribofuranosyl)-3-(2-oxo-propyl)-6H-imidazo[
TNU0005-5mg	6-(2-O-Methyl-beta-D-ribofuranosyl)-3-(2-oxo-propyl)-6H-imidazo[
TNU0005-1g	6-(2-O-Methyl-beta-D-ribofuranosyl)-3-(2-oxo-propyl)-6H-imidazo[
OR1013562-01	Imidazo[1,2-C]Pyrimidin-5(6H)-One
OR1013562-02	Imidazo[1,2-C]Pyrimidin-5(6H)-One
TRC-F135300-100MG	8-Fluoro-imidazo[1,2-c]pyrimidin-5(6H)-one
TRC-F135300-1G	8-Fluoro-imidazo[1,2-c]pyrimidin-5(6H)-one
TRC-F135300-500MG	8-Fluoro-imidazo[1,2-c]pyrimidin-5(6H)-one