5-Bromo-2’-deoxy-2’-fluoro-beta-D-arabinocytidine

5-Bromo-2’-deoxy-2’-fluoro-beta-D-arabinocytidine

• CAS Number: 69123-93-9
• UNSPSC Description: 5-Bromo-2’-deoxy-2’-fluoro-beta-D-arabinocytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/5-bromo-2-deoxy-2-fluoro-beta-d-arabinocytidine.html
• Solubility: 10 mM in DMSO
• Smiles: OC[C@@H]1[C@@H](O)[C@H](F)[C@H](N(C=C2Br)C(N=C2N)=O)O1
• Molecular Weight: 324.10
• References & Citations: [1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported