2′-Deoxy-2′-fluoro-5-methyl-arabinocytidine

• UNSPSC Description:

  2′-Deoxy-2′-fluoro-5-methyl-arabinocytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/2-deoxy-2-fluoro-5-methyl-arabinocytidine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@H]1[C@H](F)[C@H](N2C=C(C)C(N)=NC2=O)O[C@@H]1CO

• Molecular Weight:

  259.23

• References & Citations:

  [1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  78636-53-0