MenA-IN-1

CAT: 0804-HY-152495Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-152495Size:1 Each
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Description
MenA IN-1 is an effective inhibitor of 1,4-dihydroxy-2-naphthoate isoprenyltransferase (MenA) from Mycobacterium tuberculosis (MTB) with an IC50 value of 13 µM and an GIC50 value of 8 µM. MenA IN-1 can be used to curb the continuous spread of tuberculosis[1].
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mena-in-1.html
Solubility
10 mM in DMSO
Smiles
CCCN(C1=CC=C(C=C1)CN2CCC(CC2)COC3=CC(OC4=CC=CC=C4)=CC=C3)C
Molecular Formula
C29H36N2O2
Molecular Weight
444.61
References & Citations
[1]Berg K, et al. SAR study of piperidine derivatives as inhibitors of 1,4-dihydroxy-2-naphthoate isoprenyltransferase (MenA) from Mycobacterium tuberculosis. Eur J Med Chem. 2023 Jan 18;249:115125.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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