N1-Methyl-2’-deoxy-2’-fluoroarabinoadenosine

N1-Methyl-2’-deoxy-2’-fluoroarabinoadenosine

• UNSPSC Description: N1-Methyl-2’-deoxy-2’-fluoroarabinoadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/n1-methyl-2-deoxy-2-fluoroarabinoadenosine.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]1[C@H](F)[C@H](N(C=N2)C3=C2C(N(C)C=N3)=N)O[C@@H]1CO
• Molecular Weight: 283.26
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported