2-Aminomethyl adenosine

2-Aminomethyl adenosine

• CAS Number: 2305415-79-4
• UNSPSC Description: 2-Aminomethyl adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/2-aminomethyl-adenosine.html
• Solubility: 10 mM in DMSO
• Smiles: NC1=NC(CN)=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3
• Molecular Weight: 296.28
• References & Citations: [1]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.|[2]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported