2-(Aminomethyl)phenol

• UNSPSC Description:

  2-(Aminomethyl)phenol (2-Hydroxybenzylamine), a selective dicarbonyl scavenger, is an antioxidant and scavanger of free radicals and isolevuglandins (IsoLGs). 2-(Aminomethyl)phenol can be used in the research of inflammation and cardiovascular disease, such as atherosclerosis, early recurrence of atrial fibrillation (AF) and arrhythmias[1][2].

• Target Antigen:

  Reactive Oxygen Species

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/2-aminomethyl-phenol.html

• Purity:

  99.45

• Solubility:

  DMSO : 50 mg/mL (ultrasonic;warming;heat to 80°C)

• Smiles:

  OC1=CC=CC=C1CN

• Molecular Weight:

  123.155

• References & Citations:

  [1]Matthew J O'Neill, et al. 2-Hydroxybenzylamine (2-HOBA) to prevent early recurrence of atrial fibrillation after catheter ablation: protocol for a randomized controlled trial including detection of AF using a wearable device. |[2]Huan Tao, et al. Scavenging of reactive dicarbonyls with 2-hydroxybenzylamine reduces atherosclerosis in hypercholesterolemic Ldlr -/- mice.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, stored under nitrogen)

• Clinical Information:

  Phase 2

• CAS Number:

  932-30-9