N-[[4-(Trifluoromethyl)phenyl]methyl]adenosine

N-[[4-(Trifluoromethyl)phenyl]methyl]adenosine

• CAS Number: 722505-71-7
• UNSPSC Description: N-[[4-(Trifluoromethyl)phenyl]methyl]adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/n-4-trifluoromethyl-phenyl-methyl-adenosine.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C3=NC=NC(NCC4=CC=C(C(F)(F)F)C=C4)=C3N=C2
• Molecular Weight: 425.36
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.|[2]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported