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1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

CAT:
804-HY-136658-01
Size:
1 mg

For Laboratory Research Only. Not for Clinical or Personal Use.

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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea - image 1

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

  • UNSPSC Description:

    STAT3-IN-7 is a Sorafenib analogue and potently inhibits the phosphorylation of STAT3. STAT3-IN-7 induces cell apoptosis through SHP-1 dependent STAT3 inactivation. STAT3-IN-7 does not inhibit kinase activity and has anticancer effects[1].

  • Target Antigen:

    Apoptosis; STAT

  • Type:

    Reference compound

  • Related Pathways:

    Apoptosis;JAK/STAT Signaling;Stem Cell/Wnt

  • Field of Research:

    Cancer

  • Assay Protocol:

    https://www.medchemexpress.com/stat3-in-7.html

  • Smiles:

    O=C(NC1=CC=C(OC2=CC=C(C#N)C=C2)C=C1)NC3=CC=C(Cl)C(C(F)(F)F)=C3

  • Molecular Weight:

    431.80

  • References & Citations:

    [1]Chun-Yu Liu, et al. Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells. Breast Cancer Res. 2013;15(4):R63.

  • Shipping Conditions:

    Room Temperature

  • CAS Number:

    1313019-65-6

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Alternative Products

CAT

Name

PC108723-011- (4-Chloro-3- (Trifluoromethyl) Phenyl) -3- (4- (4-Cyanophenoxy) Phenyl) Urea
MBS3616165-011-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
MBS57732851-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
PC108739-011- (4-Chloro-3- (Trifluoromethyl) Phenyl) -3- (3- (4-Cyanophenoxy) Phenyl) Urea
T22424-011-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phen
sc-3964161-[4-Chloro-3-(trifluoromethyl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea
TRC-C422225-100MG1-(4-Chloro-3-(trifluoromethyl)phenyl)urea
sc-3963491-[3,5-Bis(trifluoromethyl)phenyl]-3-[4-chloro-3-(trifluoromethyl)phenyl]urea
PC101148-011,3-Bis (4- (trifluoromethyl) phenyl) urea
TRC-C142345-50MGRegorafenib (1-(4-Chloro-3-(trifluoromethyl)phenyl)urea)dimer