3’-Deoxy-3’-fluoro-N6-methyladenosine

3’-Deoxy-3’-fluoro-N6-methyladenosine

• CAS Number: 122654-27-7
• UNSPSC Description: 3’-Deoxy-3’-fluoro-N6-methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/3-deoxy-3-fluoro-n6-methyladenosine.html
• Solubility: 10 mM in DMSO
• Smiles: F[C@H]1[C@@H](O)[C@H](N(C=N2)C3=C2C(NC)=NC=N3)O[C@@H]1CO
• Molecular Weight: 283.26
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported