3’-Deoxy-3’-fluoro-xylo-N6-(m-methoxybenzyl)adenosine

• UNSPSC Description:

  3’-Deoxy-3’-fluoro-xylo-N6-(m-methoxybenzyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/3-deoxy-3-fluoro-xylo-n6-m-methoxybenzyl-adenosine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@@H]1[C@@H](F)[C@@H](CO)O[C@H]1N(C=N2)C3=C2C(NCC4=CC=CC(OC)=C4)=NC=N3

• Molecular Weight:

  389.38

• References & Citations:

  [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported