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BPDA2

CAT: 0804-HY-152208-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-152208-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BPDA2 is a highly selective and competitive active site SHP2 inhibitor with IC50s of 92.0 nM, 33.39 μM, 40.71 μM for SHP2, SHP1, SHP1B, respectively. DBDA2 downregulates mitogenic and cell survival signaling and RTK expression. BPDA2 suppresses SHP2 mediated signaling and breast cancer cell phenotypes[1].
CAS Number
2907659-86-1
UNSPSC
12352005
Target
SHP1; SHP2
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bpda2.html
Purity
99.30
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCOC1=CC=C(C=C1C(O)=O)C2=CC=C(C=C2)CC(O)=O
Molecular Formula
C24H30O5
Molecular Weight
398.49
References & Citations
[1]Dhanaji M Lade, et al. Design and synthesis of improved active-site SHP2 inhibitors with anti-breast cancer cell effects. Eur J Med Chem. 2023 Feb 5;247:115017.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
M36541-01BPDA2

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