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BPDA2

CAT: 0931-T73552-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T73552-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2907659-86-1
Target
Phosphatase
Related Pathways
Metabolism
Purity
0.998
Bioactivity
BPDA2 is a highly selective and competitive SHP2 inhibitor, exhibiting IC50 values of 92.0 nM for SHP2, and 33.39 μM and 40.71 μM for SHP1 and SHP1B, respectively. This compound effectively downregulates mitogenic and cell survival signaling, including reducing expression of receptor tyrosine kinases (RTKs) . Furthermore, BPDA2 suppresses SHP2-mediated signaling, leading to the inhibition of breast cancer cell phenotypes [1].
Smiles
O=C(O)C=1C=C(C=CC1OCCCCCCCCC)C2=CC=C(C=C2)CC(=O)O
Molecular Formula
C24H30O5
Molecular Weight
398.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
M36541-01BPDA2

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