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DRP1i27

CAT: 0804-HY-152086-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-152086-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DRP1i27 is a potent inhibitor of human Drp1 (dynamin-related protein 1) . DRP1i27 binds to the GTPase site of Drp1, with hydrogen bonds to Gln34 and Asp218. DRP1i27 targets Drp1-mediated mitochondrial fission in cell line models and protects against simulated ischemia-reperfusion injury[1].
CAS Number
1453028-33-5
UNSPSC
12352005
Target
Dynamin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/drp1i27.html
Purity
99.36
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=C(NC=N1)CN2C[C@@H]3CC[C@@H](N(C3)CC4=CC=C(O4)C5=NNC=C5)C2
Molecular Formula
C20H26N6O
Molecular Weight
366.46
References & Citations
[1]Rosdah AA, et al. A novel small molecule inhibitor of human Drp1. Sci Rep. 2022 Dec 13;12 (1) :21531.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T73456-01DRP1i27

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