SARS-CoV-2-IN-36

SARS-CoV-2-IN-36

• UNSPSC Description: SARS-CoV-2-IN-36 is a potent SARS-CoV-2 Mpro (SARS-CoV) inhibitor with an IC50 of 2.37 μM and a Kd of 1.19 μM in enzymatic assays. SARS-CoV-2-IN-36 shows antiviral activity against UC-1074, RG2674, and NVDBB-2220 SARS-CoV-2 variants in Vero cells[1].
• Target Antigen: SARS-CoV
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/sars-cov-2-in-36.html
• Solubility: 10 mM in DMSO
• Smiles: [H]C(C(N[C@H](C(N[C@@H](CC1=CNC=N1)C=O)=O)CC2=CC=CC=C2)=O)N
• Molecular Weight: 343.38
• References & Citations: [1]Simone Di Micco, et al. Rational design of the zonulin inhibitor AT1001 derivatives as potential anti SARS-CoV-2. Eur J Med Chem. 2022 Dec 15;244:114857.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported